Variant-beta luteinizing hormone is not associated with poor ovarian response to controlled ovarian hyperstimulation

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Variant-beta luteinizing hormone is not associated with poor ovarian response to controlled ovarian hyperstimulation

BACKGROUND The most common genetic variant of luteinizing hormone (LH), variant-betaLH, has a different bioactivity than the wildtype. Carrying the variant allele was associated with an increased consumption of exogenous gonadotropin to achieve optimal ovarian response for in vitro fertilization procedures (IVF). The aim of this study was to examine if variant-betaLH was also more common in pat...

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the luteinizing hormone beta-subunit exon 3 (gly102ser) gene mutation and ovarian responses to controlled ovarian hyperstimulation

background: despite extensive progress in ivf techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (coh). recent studies show the effects of individual genetic variability on coh outcome. objective: to evaluate the correlation between lhβ g1502a polymorphisms in exon 3 of the lh gene and ovarian response to coh. materials and m...

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The luteinizing hormone beta-subunit exon 3 (Gly102Ser) gene mutation and ovarian responses to controlled ovarian hyperstimulation

BACKGROUND Despite extensive progress in IVF techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (COH). Recent studies show the effects of individual genetic variability on COH outcome. OBJECTIVE To evaluate the correlation between LHβ G1502A polymorphisms in exon 3 of the LH gene and ovarian response to COH. MATERIALS AND...

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Association between the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) rs4073366 polymorphism and ovarian hyperstimulation syndrome during controlled ovarian hyperstimulation

BACKGROUND The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH). METHODS This was a prospective study of 172 patients undergoing COH at the Fertility and IVF Center at GWU. DNA was isolated from blood samples and a regi...

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Roles of follicle stimulating hormone and luteinizing hormone in controlled ovarian hyperstimulation.

With the advent of recombinant follicle stimulating hormone (FSH) and luteinizing hormone (LH), free from contamination with each other (Loumaye et al., 1995), it is possible to dissect the individual contributions of FSH and LH to the regulation of ovarian function and to define optimal gonadotrophin usage in controlled ovarian hyperstimulation (COH) (Hillier, 1994). Basic and clinical researc...

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ژورنال

عنوان ژورنال: Reproductive Biology and Endocrinology

سال: 2014

ISSN: 1477-7827

DOI: 10.1186/1477-7827-12-20